Documentation
Understand thalassemia, screen for it, and connect with the right specialist.
Introductory video
A short video explaining the disease and the most important medical guidelines:
Definition of Thalassemia
Thalassemia
Add a video URL in INTRO_VIDEO_URL to embed it here.Definition of thalassemia
Thalassemia is a hereditary hematological disorder characterized by impaired hemoglobin synthesis. It results from genetic mutations affecting globin chain production, leading to reduced oxygen-carrying capacity and varying degrees of anemia. The disorder follows an autosomal recessive inheritance pattern, requiring the presence of defective genes from both parents for severe manifestation.
Classification of Thalassemia
Alpha Thalassemia
Caused by reduced or absent production of alpha-globin chains. Clinical severity depends on the number of affected genes, ranging from asymptomatic carriers to severe conditions such as Hemoglobin Bart's hydrops fetalis.
Beta Thalassemia
Results from mutations affecting beta-globin chain synthesis. It is categorized into:
- Beta Thalassemia Minor (Trait)
- Beta Thalassemia Intermedia
- Beta Thalassemia Major (Cooley's Anemia)
Symptoms of Thalassemia
Your experience will depend on the type of thalassemia you have and its severity:
- You likely won't have symptoms if you're missing one alpha gene. If you're missing two alpha genes or one beta gene, you may be asymptomatic. Or, you may have mild anemia symptoms, like fatigue.
Beta thalassemia intermedia may cause mild anemia or moderate symptoms such as:
- Growth problems.
- Delayed puberty.
- Bone abnormalities (like osteoporosis).
- Enlarged spleen.
In some cases, surgery may be needed to correct bone problems or to remove the spleen if it becomes too large.
- Severe thalassemia may cause anemia from birth or early childhood.
- Hemoglobin H disease and beta thalassemia major can lead to lifelong severe anemia, often appearing by age 2.
Additional symptoms may include:
- Poor appetite.
- Pale or yellowish skin (jaundice).
- Urine that's dark or tea-colored.
- Irregular bone structure in your face.
Thalassemia Minor vs. Iron-Deficiency Anemia
| Feature | Thalassemia Minor | Iron-Deficiency Anemia |
|---|---|---|
| Hemoglobin | Mild | Varies |
| MCV | Low | Low |
| Severity | Mild | Mild to severe |
| RBC Count | Normal or high | Normal or low |
| Mentzer Index | Low | High |
| Serum Iron | Normal | Low |
| Ferritin | Normal | Low |
| Response to Iron Therapy | Not recommended | Improves |
| Diagnosis | Genetic testing | Observe |
About this tool
Thalassemia Detection is an AI-powered web application that screens blood-test results for thalassemia indicators. Upload a lab report and Gemini AI returns a thalassemia score, a confidence level, and a plain-language recommendation — helping you decide whether to seek confirmatory testing from a specialist.
Getting started
Open the predictor
Go to the home page or click "Try Now" to reach the Thalassemia prediction tool.
Upload a file
Drag & drop or select a blood-test file (CSV, XLSX, JSON, TXT) or a lab report image / PDF.
Run the prediction
Click "Run Prediction". The file is analysed by Gemini AI to screen for thalassemia indicators.
Review the result
Read the thalassemia score, AI confidence, recommendation, and explanation — then consult a specialist.
Understanding your results
Each prediction includes a thalassemia score from 0 to 10. The colour bands below show how to read it:
Finding a doctor
Browse our directory of hematology and thalassemia specialists. Search by name, hospital, or city, filter by specialty, then book an appointment or contact them directly.
Browse doctorsFrequently asked questions
Structured data files (CSV, XLSX, JSON, TXT) containing blood-test values, or images / PDFs of a lab report (PNG, JPG, WEBP, GIF, PDF).
The model returns a score from 0 (normal) to 10 (strong trait) together with a confidence level. Use the colour legend above to interpret where a result falls.
Open the Doctors page from the top navigation to browse hematologists, pediatric hematologists, and genetic counselors, then book or contact one directly.